Talk to your doctor before taking any medicine for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others. Taking any of these drugs with Cymbalta may cause you to bruise or bleed easily.
Before taking Duloxetine, tell your doctor if you are using any of the following medicines:
a blood thinner such as warfarin (Coumadin);
cimetidine (Tagamet); a diuretic (water pill);
fluvoxamine (Luvox); linezolid (Zyvox); lithium (Lithobid, Eskalith); St. John's wort;
tramadol (Ultram); tryptophan (sometimes called L-tryptophan); an antibiotic such as ciprofloxacin (Cipro); almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig); or
any other antidepressant such as desipramine (Norpramin), fluoxetine (Prozac, Sarafem), paroxetine (Paxil), and others.